Crohn’s disease patients have specific IgG antibodies to human bacterial flagellins

Last year, Charles O. Elson, M.D., demonstrated a potential preventive treatment for Crohn’s disease, a form of inflammatory bowel disease. He used a mouse model that included immune-reactive T cells from patients with Crohn’s disease in a flagellin peptide-specific immunotherapy. This study provided proof-of-principle that a flagellin-directed immunotherapy might provide similar benefits in patients. Now […]

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Cardiovascular health is poorest among American adults in the Southern U.S.

In a recent study published in the Mayo Clinic Proceedings, University of Alabama at Birmingham researchers found that there is significant geographic heterogeneity in the distribution of cardiovascular disease risk factors such as diabetes, hypertension, high blood cholesterol levels, obesity, smoking, lack of physical activity and unhealthy diet, across the United States. These risk factors […]

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Post-surgical delirium higher in older adults who exhibit depressive symptoms

Screening for even mild depressive symptoms before hip fracture repair may be helpful in predicting which patients are at higher risk of developing delirium after emergency surgery, according to results of a new study by researchers from Johns Hopkins Medicine. The researchers say their findings also add to evidence that symptoms of depression and postoperative […]

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5 facts about celiac disease

For people with celiac disease, foods as seemingly wholesome as whole grain bread can be dangerous. Why? Having celiac means that exposure to gluten—a protein found in grains such as wheat, barley and rye—causes the immune system to attack the small intestine, damaging its lining and potentially preventing the body from absorbing enough important vitamins, […]

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